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PASTA domain
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PASTA domain : ウィキペディア英語版
PASTA domain

The PASTA domain is a small protein domain that can bind to beta-lactam rings found in antibiotics. The domain was initially discovered in 2002 by Yeats and colleagues as a region of sequence similarity found in penicillin binding proteins and PknB-like kinases found in some bacteria. The name is an acronym derived from PBP and Serine/Threonine kinase Associated domain.
==Structure==
The PASTA domain adopts a structure composed of an alpha-helix followed by three beta strands. Recent structural studies show that the extracellular region of PknB that is composed of four PASTA domains shows a linear arrangement of the domains.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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